Divarasib (GDC-6036)
Divarasib (GDC-6036, RG6330) is a KRAS G12C inhibitor that binds irreversibly to switch II pocket of KRAS G12C (when in the inactive GDP-bound state) thereby blocking GTP binding and activation.
| Trivial name | RG6330 |
| Catalog Number | E1187 |
| Molecular Formula | C8H4N4O6 |
| CAS# | 2417987-45-0 |
| SMILES | O=C1NC2=CC(=C(C=C2NC1=O)[N;v5](=O)=O)[N;v5](=O)=O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/gdc6036.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e1187-gdc6036-chemical-structure.png |