UGT8-IN-1
UGT8-IN-1 is a brain-penetrable and orally active inhibitor of ceramide galactosyltransferase enzyme (UGT8). UGT8-IN-1 targets sulfatide metabolism resulting in ceramide-induced lethal mitophagy and subsequent cancer cell death in vitro, and reduces tumour growth in mutant Kras; Gnas allografts.
Catalog Number | E4592 |
Molecular Formula | C28H36N4O6S2 |
CAS# | 2414349-93-0 |
SMILES | CC1CC(CN(C1)S(=O)(=O)C2=CC3=C(C=C2)C(=C4C=CC(=CC4=C3N=O)S(=O)(=O)N5CC(CC(C5)C)C)NO)C |
Size | 1mg |
Supplier Page | http://www.selleckchem.com/products/ugt8-in-1.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4592-UGT8-IN-1-chemical-structure.png |