NIC-12 | MedChemExpress (MCE)
NIC-12 is a potent NLRP3 inhibitor. NIC-12 selectively reduces circulating IL-1ß levels in the LPS-endotoxemia mice model. NIC-12 inhibits NLRP3 inflammasome activation in mouse macrophages[1].
| Trivial name | NIC-12 |
| Catalog Number | HY-158093 |
| Research Area | Inflammation/Immunology |
| CAS# | 2409826-23-7 |
| Purity | ≥98.0% |
| SMILES | CC(C1=NN(C(C2=CC3=C(N21)C=C(S3)Cl)=O)CC(N[C@@H]4CCCN(C4)CC5CC5)=O)C |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/nic-12.html |