BO-264

BO-264 is a potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3) with IC50 of 188 nM and Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. BO-264 induces SAC-dependent mitotic arrest, apoptosis and DNA damage with antitumor activities.

Price Not Available 25mg BO-264 Supplier Page

Trivial name	N/A
Catalog Number	S8965
Molecular Formula	C18H19N5O3
CAS#	2408648-20-2
SMILES	COC1=CC=C(C=C1)C2=NOC(=C2)NC3=NC(=NC=C3)N4CCOCC4
Size	25mg
Supplier Page	http://www.selleckchem.com/products/bo-264.html
Additional Information	https://file.selleck.cn/downloads/struct/s8965-bo-264-chemical-structure.gif