CRN04894 | MedChemExpress (MCE)
CRN04894 (compound 17h) is an orally active MC2R antagonist that demonstrates in vivo efficacy in rat model of adrenocorticotropic hormone (ACTH)-stimulated corticosterone secretion[1]. CRN04894 binds to human or rat MC2R with KB values of 0.34 nM and 0.23 nM, respsectively[1].
| Trivial name | CRN04894 |
| Catalog Number | HY-158081 |
| Research Area | Endocrinology |
| CAS# | 2392970-97-5 |
| Purity | ≥98.0% |
| SMILES | O=C(N1C[C@H](N(C2=C(N=C(C3=C(C=CC=C3)OCC)C=C2)C(N[C@H]4C5CCN(CC5)C4)=O)CC1)CC)C6(CCC6)C(F)(F)F |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/crn04894.html |