SR-4835

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

Price Not Available 100mg SR-4835 Supplier Page

Trivial name	N/A
Catalog Number	S8894
Molecular Formula	C21H20Cl2N10O
CAS#	2387704-62-1
SMILES	CN1C=C(C=N1)N2C=NC3=C(N=C(N=C32)N4CCOCC4)NCC5=NC6=CC(=C(C=C6N5)Cl)Cl
Size	100mg
Supplier Page	http://www.selleckchem.com/products/sr-4835.html
Additional Information	https://file.selleck.cn/downloads/struct/sr-4835-chemical-structure-s8894.gif