(32-Carbonyl)-RMC-5552
(32-Carbonyl)-RMC-5552 is a highly effective mTOR inhibitor, exhibiting inhibitory effects on both mTORC1 and mTORC2 substrate phosphorylation. Specifically, it significantly suppresses the phosphorylation of p-P70S6K-(T389), p-4E-BP1-(T37/36), and p-AKT1/2/3-(S473) with pIC50 values > 9, >9 and 8~9, respectively (patent WO2019212990A1, example 2).
![](https://smallmolecules.com/sm/wp-content/uploads/products/targetmol/wk/wkgfd2prkf2eje8eaaaaacg3v5c860.jpg)
Catalog Number | T39958 |
Molecular Formula | C93H134N10O24 |
CAS# | 2382768-55-8 |
SMILES | [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C/C=C\C=C(C)/[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N2CCc3cc(Cn4nc(-c5ccc6oc(N)nc6c5)c5c(N)ncnc45)ccc3C2)[C@@H](C1)OC |c:47,49,t:32,51| |
Size | 10 mg |
Supplier Page | https://www.targetmol.com/compound/(32-carbonyl)-rmc-5552 |
Additional Information | https://www.targetmol.com/datasheet/T39958 |