Retatrutide
Retatrutide (LY3437943) acts as a triple agonist peptide of the glucagon receptor (GCGR), glucagon-like peptide-1 receptor (GLP-1R) and glucosedependent insulinotropic polypeptide receptor (GIPR). Retatrutide binds to human GCGR, GLP-1R, and GIPR with EC50 values of 5.79, 0.775 nM, and 0.0643, respectively. Retatrutide has the potential for use in research on obesity.
| Trivial name | LY3437943 |
| Catalog Number | P1230 |
| Molecular Formula | C20H23N7O6.Ca |
| CAS# | 2381089-83-2 |
| Inchi | InChI=1S/C20H25N7O6.Ca/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);/q;2/p-2/t12-,13-;/m0./s1 |
| Inchi Key | VWBBRFHSPXRJQD-QNTKWALQSA-L |
| SMILES | CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2] |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/retatrutide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/P1230-Retatrutide-LY3437943-chemical-structure-tube.png |