Ac-FLTD-CMK
Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1, caspases-4, caspases-5, and caspases-11 , but not the apoptotic caspases such as caspase-3.
| Catalog Number | OPO-005 |
| Alternative Name(s) | N-acetyl-Phe-Leu-Thr-Asp-chloromethylketone, GSDMD-derived inhibitor |
| Molecular Formula | C26H37ClN4O8 |
| CAS# | 2376255-48-8 |
| Purity | >95% |
| Inchi | InChI=1S/C26H37ClN4O8/c1-14(2)10-19(30-24(37)20(28-16(4)33)11-17-8-6-5-7-9-17)25(38)31-23(15(3)32)26(39)29-18(12-22(35)36)21(34)13-27/h5-9,14-15,18-20,23,32H,10-13H2,1-4H3,(H,28,33)(H,29,39)(H,30,37)(H,31,38)(H,35,36)/t15-,18+,19+,20+,23+/m1/s1 |
| Inchi Key | UCWNTWGHVCSMJP-WPUDHWPRSA-N |
| SMILES | C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CCl)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C)O |
| Size | Inquiry |
| Supplier Page | https://www.creative-peptides.com/product/ac-fltd-cmk-item-opo-005-40682.html |