C5aR1 antagonist 2 | MedChemExpress (MCE)
C5aR1 antagonist 2 (Compound 6a) is an orally active C5a receptor 1 (C5aR1) antagonist that shows efficacy in inhibiting the C5a-induced neutrophil count increase. C5aR1 antagonist 2 is potent in the DISCO and migration assays, with IC50 values of 21 and 3 nM, respectively. C5aR1 antagonist 2 can be used for the research of acute and chronic inflammatory diseases[1].
| Trivial name | C5aR1 antagonist 2 |
| Catalog Number | HY-163379 |
| Research Area | Inflammation/Immunology |
| CAS# | 2365161-92-6 |
| Purity | ≥98.0% |
| SMILES | O=C1N(CC2=C(C(F)(F)F)C=CC=C2)C3=C(N1C4CCN(CC4)C5=C(C)C=CC=C5C)C=CC=C3OC |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/c5ar1-antagonist-2.html |