GSK8612
GSK8612 is a highly potent and selective inhibitor for TBK1 (Tank-binding Kinase-1) with pKd of 8.0. Within 10-fold affinity with respect to TBK1, no off-targets of GSK8612 could be identified.
| Trivial name | N/A |
| Catalog Number | S8872 |
| Molecular Formula | C17H17BrF3N7O2S |
| CAS# | 2361659-62-1 |
| Inchi | InChI=1S/C17H17BrF3N7O2S/c1-10-14(8-28(27-10)9-17(19,20)21)25-16-24-7-13(18)15(26-16)23-6-11-2-4-12(5-3-11)31(22,29)30/h2-5,7-8H,6,9H2,1H3,(H2,22,29,30)(H2,23,24,25,26) |
| Inchi Key | FFPHMUIGESPOTK-UHFFFAOYSA-N |
| SMILES | CC1=NN(C=C1NC2=NC=C(C(=N2)NCC3=CC=C(C=C3)S(=O)(=O)N)Br)CC(F)(F)F |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/gsk8612.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk8612-chemical-structure-s8872.gif |