Decitabine
Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.
| Trivial name | Deoxycytidine, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716 |
| Catalog Number | S1200 |
| Molecular Formula | C8H12N4O4 |
| CAS# | 2353-33-5 |
| Inchi | InChI=1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1 |
| Inchi Key | XAUDJQYHKZQPEU-KVQBGUIXSA-N |
| SMILES | C1C(C(OC1N2C=NC(=NC2=O)N)CO)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Decitabine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Decitabine-chemical-structure-S1200.gif |