Decitabine
Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS). Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.
| Trivial name | Deoxycytidine, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR,NSC 127716 |
| Catalog Number | S1200 |
| Molecular Formula | C19H16BrFN6O2 |
| CAS# | 2353-33-5 |
| Inchi | InChI=1S/C19H16BrFN6O2/c1-28-17-9-13-16(10-18(17)29-7-6-27-5-4-24-26-27)22-11-23-19(13)25-15-3-2-12(20)8-14(15)21/h2-5,8-11H,6-7H2,1H3,(H,22,23,25) |
| Inchi Key | YBTGTVGEKMZEQX-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Br)F)OCCN4C=CN=N4 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/Decitabine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Decitabine-chemical-structure-S1200.gif |