GA-017

GA-017 inhibits theserine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10±0.79 and 3.92±0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58±0.11 and 0.25±0.03 nM, respectively.

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Catalog Number	E1145
Molecular Formula	C18H21N3O4
CAS#	2351906-74-4
SMILES	CC\C(=N\NC(=O)NCC1=CC(=CC=C1)O)C2=C(O)C(=C(O)C=C2)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/ga-017.html
Additional Information	https://file.selleck.cn/downloads/struct/e1145-ga-017-chemical-structure.gif