ZT-12-037-01
ZT-12-037-01 is a specific and ATP-competitive STK19 inhibitor with IC50s of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N), respectively. It displays extremely high kinase selectivity using KINOMEscan against a panel of 468 diverse kinases using an in vitro ATP-site competition binding assay at 1 μM.
| Trivial name | N/A |
| Catalog Number | S8864 |
| Molecular Formula | C21H31N5O2 |
| CAS# | 2328073-61-4 |
| Inchi | InChI=1S/C21H31N5O2/c1-13(2)26-9-7-15(8-10-26)22-20-16-11-18(27-3)19(28-4)12-17(16)24-21(25-20)23-14-5-6-14/h11-15H,5-10H2,1-4H3,(H2,22,23,24,25) |
| Inchi Key | AMAQJTHMSLYMFT-UHFFFAOYSA-N |
| SMILES | CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)NC4CC4 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/zt-12-037-01.html |
| Additional Information | https://file.selleck.cn/downloads/struct/zt-12-037-01-chemical-structure-s8864.gif |