Lapatinib
Lapatinib is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively. Lapatinib induces ferroptosis and autophagic cell death.
| Trivial name | GSK572016, GW2016 |
| Catalog Number | S2111 |
| Molecular Formula | C27H28N4O3S2 |
| CAS# | 231277-92-2 |
| Inchi | InChI=1S/C27H28N4O3S2/c1-19-16-22(11-14-25(19)20-9-12-24(13-10-20)36(2,32)33)34-18-26-29-30-27(35-23-7-3-4-8-23)31(26)21-6-5-15-28-17-21/h5-6,9-17,23H,3-4,7-8,18H2,1-2H3 |
| Inchi Key | UJGTUKMAJVCBIS-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)OCC2=NN=C(N2C3=CN=CC=C3)SC4CCCC4)C5=CC=C(C=C5)S(=O)(=O)C |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/lapatinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Lapatinib-chemical-structure-s2111.gif |