DMX-5084
DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.
| Trivial name | N/A |
| Catalog Number | S0268 |
| Molecular Formula | C21H19N3O3 |
| CAS# | 2306178-56-1 |
| SMILES | COCCOC1=CC=C(C=C1)C2=CN(C3=C2C(=O)NC=N3)C4=CC=CC=C4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/dmx-5084.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0268-dmx-5084-chemical-structure.gif |