KRAS G12C inhibitor 61 | MedChemExpress (MCE)

KRAS G12C inhibitor 61 (Example 3) inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. KRAS G12C inhibitor 61 can be used for research of pancreatic, colorectal, and lung cancers[1].

Trivial name KRAS G12C inhibitor 61
Catalog Number HY-156549
Research Area Cancer
CAS# 2300967-40-0
Purity ≥98.00%
SMILES O=C1N=C(N2[C@@H](C)CN([C@H](C)C2)C(C=C)=O)C3=C(N1C4=C(C)C=CN=C4C(C)C)N=C(C5=C(N)C=CC=C5F)C(Cl)=C3
PubChem Chemical Structure ID 138460837
Size 1 mg
Supplier Page https://www.medchemexpress.com/kras-g12c-inhibitor-61.html