Bobcat339

Bobcat339 is a cytosine-based small molecule inhibitor of TET enzyme with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively, reducing DNA 5hmC levels in hippocampal neurons. It is useful in epigenetics research and a potential starting point for therapeutics targeting DNA methylation and gene transcription.

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Catalog Number	E4795
Molecular Formula	C23H27N7O3S2
CAS#	2280037-51-4
Inchi	InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
Inchi Key	LHNIIDJUOCFXAP-UHFFFAOYSA-N
SMILES	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Size	5mg
Supplier Page	http://www.selleckchem.com/products/bobcat339-e4795.html
Additional Information	https://file.selleck.cn/downloads/struct/E4795-Bobcat339-chemical-structure.png

Bobcat339 hydrochloride

Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe.

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Trivial name	Bobcat339 HCl
Catalog Number	S6682
CAS#	2436747-44-1
Size	5mg
Supplier Page	http://www.selleckchem.com/products/bobcat339.html
Additional Information	https://file.selleck.cn/downloads/struct/s6682-bobcat339-hydrochloride-chemical-structure.gif