Bobcat339 hydrochloride
Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe.
| Trivial name | Bobcat339 HCl |
| Catalog Number | S6682 |
| Molecular Formula | C16H13Cl2N3O |
| CAS# | 2436747-44-1 |
| Inchi | InChI=1S/C16H12ClN3O/c17-14-10-20(16(21)19-15(14)18)13-8-4-7-12(9-13)11-5-2-1-3-6-11/h1-10H,(H2,18,19,21) |
| Inchi Key | QMGYGOOYCNTEQO-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C2=CC(=CC=C2)N3C=C(C(=NC3=O)N)Cl |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/bobcat339.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s6682-bobcat339-hydrochloride-chemical-structure.gif |