Pomalidomide-PEG1-C2-N3| ChemScene
Pomalidomide-PEG1-C2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology. Pomalidomide-PEG1-C2-N3 can be used to design a selective CDK6 PROTAC degrader CP-10. CP-10 induces the degradation of CDK6 with an DC50 of 2.1 nM.
| Trivial name | Pomalidomide-PEG1-C2-N3 |
| Catalog Number | CS-0101170 |
| Alternative Name(s) | Cereblon Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 50 |
| Molecular Formula | 386.36 |
| CAS# | 2271036-44-1 |
| Purity | >98% |
| Condensed Formula | C17H18N6O5 |
| Size | 25mg |
| Supplier Page | www.chemscene.com/2271036-44-1.html |