Emapunil (AC 5216)
Emapunil (AC-5216, 18 kiloDalton Translocator Protein, XBD173) is a novel mitochondrial benzodiazepine receptor/translocator protein (MBR/TSPO) ligand. Emapunil(AC-5216) showes high affinity for MBRs prepared from rat whole brain with Ki of 0.297 nM and IC50 of 3.04 nM and 2.73 nM at rat glioma cells and human glioma cells, respectively.
| Trivial name | 18 kiloDalton Translocator Protein, XBD173 |
| Catalog Number | S2592 |
| Molecular Formula | C23H23N5O2 |
| CAS# | 226954-04-7 |
| Inchi | InChI=1S/C23H23N5O2/c1-3-27(15-17-10-6-4-7-11-17)20(29)16-28-22-19(26(2)23(28)30)14-24-21(25-22)18-12-8-5-9-13-18/h4-14H,3,15-16H2,1-2H3 |
| Inchi Key | NBMBIEOUVBHEBM-UHFFFAOYSA-N |
| SMILES | CCN(CC1=CC=CC=C1)C(=O)CN2C3=NC(=NC=C3N(C2=O)C)C4=CC=CC=C4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/emapunil.html |
| Additional Information | https://file.selleck.cn/downloads/struct/emapunil-chemical-structure-s2592.gif |