JND3229
JND3229 is a potent reversible inhibitor of EGFRC797S with an IC50 value of 5.8 nM. JND3229 also potently suppresses EGFRL858R/T790M and EGFRWT with IC50 values of 30.5 nM and 6.8 nM, respectively.
Trivial name | N/A |
Catalog Number | S6881 |
Molecular Formula | C33H41ClN8O2 |
CAS# | 2260886-64-2 |
SMILES | CCC(=O)NC1CCC(CC1)N2C3=NC(=NC=C3CN(C2=O)C4=CC=CC=C4Cl)NC5=CC(=C(C=C5)N6CCN(CC6)C)C |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/jnd3229.html |
Additional Information | https://file.selleck.cn/downloads/struct/s6881-jnd3229-chemical-structure.gif |