Dooku1

Dooku1 is an analog of Yoda1 with antagonist activity against mechanosensitive Piezo1 channel. Dooku1 inhibits 2 μM Yoda1-induced Ca2+-entry with IC50 of 1.3 μM in HEK 293 cells and 1.5 μM in HUVECs, respectively.

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Trivial name	N/A
Catalog Number	S2953
Molecular Formula	C13H9Cl2N3OS
CAS#	2253744-54-4
SMILES	ClC1=C(CSC2=NN=C(O2)C3=CC=C[NH]3)C(=CC=C1)Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/dooku1.html
Additional Information	https://file.selleck.cn/downloads/struct/s2953-dooku1-chemical-structure.gif