(3R,8S)-Falcarindiol

Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) is a natural polyacetylene compound found rich in many plants of the Umbelliferae family. Falcarindiol suppresses LPS-stimulated expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β). Falcarindiol attenuates the LPS-induced activation of JNK, ERK, STAT1, and STAT3 signaling molecules.

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Trivial name	FAD, (3R,8S)-Falcarindiol, FaDOH
Catalog Number	S3292
Molecular Formula	C26H23N7O2
CAS#	225110-25-8
Inchi	InChI=1S/C26H23N7O2/c1-2-6-21(34)32-15-5-7-19(32)25-31-22(23-24(27)29-14-16-33(23)25)17-9-11-18(12-10-17)26(35)30-20-8-3-4-13-28-20/h3-4,8-14,16,19H,5,7,15H2,1H3,(H2,27,29)(H,28,30,35)/t19-/m0/s1
Inchi Key	WDENQIQQYWYTPO-IBGZPJMESA-N
SMILES	CC#CC(=O)N1CCCC1C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5
Size	1mg
Supplier Page	http://www.selleckchem.com/products/3r-8s-falcarindiol.html
Additional Information	https://file.selleck.cn/downloads/struct/s3292-falcarindiol-chemical-structure.gif