Ripasudil free base
Ripasudil free base (K-115 free base) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.
Trivial name | K-115 free base |
Catalog Number | E7747 |
Molecular Formula | C20H27N3O6.HCl |
CAS# | 223645-67-8 |
Inchi | InChI=1S/C20H27N3O6.ClH/c1-4-29-19(27)15(11-10-14-8-6-5-7-9-14)21-13(2)17(24)23-16(18(25)26)12-22(3)20(23)28;/h5-9,13,15-16,21H,4,10-12H2,1-3H3,(H,25,26);1H/t13-,15-,16-;/m0./s1 |
Inchi Key | LSLQGMMMRMDXHN-GEUPQXMHSA-N |
SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C(CN(C2=O)C)C(=O)O.Cl |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/ripasudil-free-base.html |
Additional Information | https://file.selleck.cn/downloads/struct/e7747-ripasudil-free-base-chemical-structure-tube.png |