MT-802

MT-802 is a potent PROTAC that induces Bruton’s tyrosine kinase (BTK) knockdown. MT-802 recruits BTK to the cereblon E3 ubiquitin ligase complex to trigger BTK ubiquitination and degradation via the proteasome. MT-802 has potential for treatment of C481S mutant chronic lymphocytic leukemia (CLL).

Price Not Available 25mg MT-802 Supplier Page
Trivial name N/A
Catalog Number S6966
Molecular Formula C41H41N9O8
CAS# 2231744-29-7
SMILES NC1=C2C(=NC=N1)[N](N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCN(CCOCCOCC(=O)NC6=CC7=C(C=C6)C(=O)N(C8CCC(=O)NC8=O)C7=O)CC5
Size 25mg
Supplier Page http://www.selleckchem.com/products/mt-802.html
Additional Information https://file.selleck.cn/downloads/struct/s6966-mt-802-chemical-structure.gif