XY028-133| ChemScene
XY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity, which consists of ligands for von Hippel-Lindau and CDK.In Vitro: XY028-133 (1 and 3 μM, 24 h) significantly decreases CDK4/6, Cyclin A, PLK1 and pRb protein levels in A375 cells.
| Trivial name | XY028-133 |
| Catalog Number | CS-0103866 |
| Molecular Formula | 1002.23 |
| CAS# | 2229974-73-4 |
| Purity | >98% |
| Condensed Formula | C53H67N11O7S |
| Size | 100mg |
| Supplier Page | www.chemscene.com/2229974-73-4.html |