FLT3-IN-3
FLT3-IN-3 is a potent inhibitor of FLT3 with IC50 values of 13 nM and 8 nM for FLT3 WT and FLT3 D835Y, respectively. FLT3-IN-3 effectively suppresses the proliferation of FLT3-ITD-positive MV4-11 and MOLM-13 cell lines at low nanomolar concentrations.
Catalog Number | S5986 |
Molecular Formula | C22H25ClFN7O2 |
CAS# | 2229050-90-0 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | CC1=CN=C(NC2CCOCC2)N=C1[N]3C=NC(=C3)C(=O)NC(CN)C4=CC(=CC(=C4)F)Cl |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/flt3-in-3.html |
Additional Information | https://file.selleck.cn/downloads/struct/S5986-FLT3-IN-3-chemical-structure.png |