1-Naphthyl PP1(1-NA-PP1)
1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.
| Trivial name | N/A |
| Catalog Number | S2642 |
| Molecular Formula | C17H15N9 |
| CAS# | 221243-82-9 |
| Inchi | InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1 |
| Inchi Key | XYDNMOZJKOGZLS-NSHDSACASA-N |
| SMILES | CC(C1=CN2C=CN=C2C=C1)N3C4=NC(=CN=C4N=N3)C5=CN(N=C5)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/1-na-pp1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/1-na-pp1-chemical-structure-s2642.gif |