1-Naphthyl PP1(1-NA-PP1)
1-Naphthyl PP1(1-NA-PP 1) is a highly selective and potent pan-PKD inhibitor with IC50 of 154.6 nM,133.4 nM and 109.4 nM for PKD1, PKD2 and PKD3, respectively. 1-Naphthyl PP1 is a selective inhibitor of Src family kinases (v-Src, c-Fyn) and the tyrosine kinase c-Abl with IC50 of 1.0 μM, 0.6 μM, 0.6 μM, 18 μM and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II, respectively.
| Trivial name | N/A |
| Catalog Number | S2642 |
| Molecular Formula | C19H19N5 |
| CAS# | 221243-82-9 |
| Inchi | InChI=1S/C19H19N5/c1-19(2,3)24-18-15(17(20)21-11-22-18)16(23-24)14-10-6-8-12-7-4-5-9-13(12)14/h4-11H,1-3H3,(H2,20,21,22) |
| Inchi Key | XSHQBIXMLULFEV-UHFFFAOYSA-N |
| SMILES | CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=CC4=CC=CC=C43)N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/1-na-pp1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/1-na-pp1-chemical-structure-s2642.gif |