Tigecycline
Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation. Tigecycline induces autophagy by downregulating the PI3K-AKT-mTOR pathway.
| Trivial name | GAR-936, WAY-GAR-936, TBG-MINO |
| Catalog Number | S1403 |
| Molecular Formula | C29H39N5O8 |
| CAS# | 220620-09-7 |
| Inchi | InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30 ,41)(H,32,35)/t12-,14-,21-,29-/m0/s1 |
| Inchi Key | FPZLLRFZJZRHSY-HJYUBDRYSA-N |
| SMILES | CC(C)(C)NCC(=O)NC1=CC(=C2CC3CC4C(C(=O)C(=C(C4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/Tigecycline.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Tigecycline-chemical-structure-S1403.gif |