Ixabepilone
Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.
| Trivial name | Azaepothilone B, BMS-247550, Aza-epothilone B |
| Catalog Number | S7930 |
| Molecular Formula | C27H42N2O5S |
| CAS# | 219989-84-1 |
| Inchi | InChI=1S/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17 +,20-,21-,22-,24-,27+/m0/s1 |
| Inchi Key | FABUFPQFXZVHFB-PVYNADRNSA-N |
| SMILES | CC1CCCC2(C(O2)CC(NC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC3=CSC(=N3)C)C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ixabepilone-bms-247550.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ixabepilone-bms-247550-chemical-structure-s7930.gif |