RMC-4550
RMC-4550 is a potent SHP-2inhibitor with an IC50 of 1.55 nM and it has no significant activity vs. 468 kinases, the catalytic domain of 15 phosphatases and other cellular targets including GPCRs, transporters and ion channels.
| Trivial name | N/A |
| Catalog Number | S8718 |
| Molecular Formula | C21H26Cl2N4O2 |
| CAS# | 2172651-73-7 |
| Inchi | InChI=1S/C21H26Cl2N4O2/c1-12-18(14-4-3-5-15(22)17(14)23)26-16(10-28)20(25-12)27-8-6-21(7-9-27)11-29-13(2)19(21)24/h3-5,13,19,28H,6-11,24H2,1-2H3/t13-,19+/m0/s1 |
| Inchi Key | IKUYEYLZXGGCRD-ORAYPTAESA-N |
| SMILES | CC1C(C2(CCN(CC2)C3=NC(=C(N=C3CO)C4=C(C(=CC=C4)Cl)Cl)C)CO1)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/rmc-4550.html |
| Additional Information | https://file.selleck.cn/downloads/struct/rmc-4550-chemical-structure-s8718.gif |