dTRIM24
dTRIM 24 is a is a selective bifunctional degrader of TRIM24 protein, with an IC50 of 337.7 nM. By leveraging the VHL (von Hippel–Lindau) E3 ligase, dTRIM24 induces proteasomal degradation of TRIM24 in a manner dependent on binding both TRIM24’s bromodomain and the VHL complex.
| Catalog Number | E1143 |
| Molecular Formula | C26H34F2N6O4S |
| CAS# | 2170695-14-2 |
| SMILES | CC1=CC(=NC(=N1)N2CCC(F)(F)CC2)NC(=O)C3=C(C=C(N[S;v6](=O)(=O)CCO)C=C3)N4CCC5(CC4)CC5 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/dtrim24.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E1143-dTRIM24-chemical-structure.png |