HS-1371
HS-1371 is a potent RIP3 kinase inhibitor with an IC50 of 20.8 nM. It binds to the ATP binding pocket of RIP3 and inhibits ATP binding to prevent RIP3 enzymatic activity in vitro.
| Trivial name | N/A |
| Catalog Number | S8775 |
| Molecular Formula | C24H24N4O |
| CAS# | 2158197-70-5 |
| Inchi | InChI=1S/C24H24N4O/c1-17-2-5-21(6-3-17)29-24-10-13-26-23-14-18(4-7-22(23)24)19-15-27-28(16-19)20-8-11-25-12-9-20/h2-7,10,13-16,20,25H,8-9,11-12H2,1H3 |
| Inchi Key | VPVLPCIBKVWFDT-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)OC2=C3C=CC(=CC3=NC=C2)C4=CN(N=C4)C5CCNCC5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/hs-1371.html |
| Additional Information | https://file.selleck.cn/downloads/struct/hs-1371-chemical-structure-s8775.gif |