SU-5402
A potent and selective inhibitor of fibroblast growth factor receptor (FGFR) (IC50 = 0.03 µM for FGFR1) and vascular endothelial growth factor receptors (VEGFR) (IC50 = 0.02 µM for VEGFR2). In addition, integrin β4-induced differentiation of neural stem cells was attenuated by SU 5402.
Catalog Number | ABS-066 |
Alternative Name(s) | 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-meth yl-1H-pyrrole-3-propanoic acid |
CAS# | 215543-92-3 |
Inchi | InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8- |
Inchi Key | JNDVEAXZWJIOKB-JYRVWZFOSA-N |
SMILES | CC1=CNC(=C1CCC(=O)O)C=C2C3=CC=CC=C3NC2=O |
Size | Inquiry |
Supplier Page | https://www.agingclocks.com/su-5402-item-1530.html |