Selpercatinib (LOXO-292)

Selpercatinib (LOXO-292, ARRY-192) is a potent and specific RET (c-RET) inhibitor with IC50 values of 1 nM, 2 nM, 2 nM, 4 nM, 2 nM, 2 nM for WT RET, RET V804M, RET V804L, RET A883F, RET M918T and RET S891A respectively.

Price Not Available 5mg Selpercatinib (LOXO-292) Supplier Page

Trivial name	ARRY-192
Catalog Number	S8781
Molecular Formula	C29H31N7O3
CAS#	2152628-33-4
Inchi	InChI=1S/C29H31N7O3/c1-29(2,37)18-39-24-9-25(28-21(10-30)13-33-36(28)17-24)20-5-6-26(31-12-20)34-15-22-8-23(16-34)35(22)14-19-4-7-27(38-3)32-11-19/h4-7,9,11-13,17,22-23,37H,8,14-16,18H2,1-3H3
Inchi Key	XIIOFHFUYBLOLW-UHFFFAOYSA-N
SMILES	CC(C)(COC1=CN2C(=C(C=N2)C#N)C(=C1)C3=CN=C(C=C3)N4CC5CC(C4)N5CC6=CN=C(C=C6)OC)O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/loxo-292.html
Additional Information	https://file.selleck.cn/downloads/struct/loxo-292-chemical-structure-s8781.gif