MD-224
A PROTAC that drives MDM2 degradation
| Catalog Number | 40960 |
| Research Area | Product Type|Biochemicals|PROTACs||Research Area|Cancer|Cell Signaling|p53 Signaling||Research Area|Cancer|Transcription Factors|p53||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors |
| Molecular Formula | C48H43Cl2FN6O6 |
| CAS# | 2136247-12-4 |
| Purity | ≥95% |
| Inchi | InChI=1S/C48H43Cl2FN6O6/c49-29-16-19-34-36(25-29)54-46(63)48(34)39(32-12-8-13-35(50)40(32)51)41(56-47(48)22-4-2-5-23-47)44(61)53-30-17-14-28(15-18-30)42(59)52-24-6-1-3-9-27-10-7-11-31-33(27)26-57(45(31)62)37-20-21-38(58)55-43(37)60/h7-8,10-19,25,37,39,41,56H,1-2,4-6,20-24,26H2,(H,52,59)(H,53,61)(H,54,63)(H,55,58,60)/t37?,39-,41+,48+/m0/s1 |
| Inchi Key | ZLGNYFOIDAVMHY-MPKOGUQCSA-N |
| SMILES | O=C1C2=CC=CC(C#CCCCNC(C(C=C3)=CC=C3NC([C@H](NC45CCCCC4)[C@@H]([C@@]56C7=CC=C(C=C7NC6=O)Cl)C8=C(C(Cl)=CC=C8)F)=O)=O)=C2CN1C9C(NC(CC9)=O)=O |
| Size | 500 µg |
| Supplier Page | https://www.caymanchem.com/product/40960 |