HSP27 inhibitor J2

HSP27 inhibitor J2 (J2) is an inhibitor of HSP27, which induces abnormal HSP27 dimers formation and suppresses the generation of HSP27 giant polymers, inhibiting the chaperone role of HSP27 and diminishing its cellular protective function. HSP27 inhibitor J2 (J2) enhances the antiproliferative activity of 17-AAG and increases the sensitivity of cisplatin-induced lung cancer cell growth inhibition.

Price Not Available 5mg HSP27 inhibitor J2 Supplier Page

Trivial name	J2
Catalog Number	S3404
Molecular Formula	C19H18F5N5O5S
CAS#	2133499-85-9
Inchi	InChI=1S/C17H17F2N5O3S.C2HF3O2/c1-17(9-28(26,27)24(2)16(20)23-17)12-7-11(4-5-13(12)19)22-15(25)14-6-3-10(18)8-21-14;3-2(4,5)1(6)7/h3-8H,9H2,1-2H3,(H2,20,23)(H,22,25);(H,6,7)/t17-;/m0./s1
Inchi Key	MNYVOIVLGITLBF-LMOVPXPDSA-N
SMILES	CC1(CS(=O)(=O)N(C(=N1)N)C)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)F)F.C(=O)(C(F)(F)F)O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/hsp27-inhibitor-j2.html
Additional Information	https://file.selleck.cn/downloads/struct/S3404-HSP27-inhibitor-J2-chemical-structure.png