ZSH-2208
ZSH‐2208 is a RARγ-selective retinoic acid analogue that exhibits potent anti-tumor effects in oesophageal squamous cell carcinoma (ESCC). It inhibits ESCC tumour-repopulating cells (TRCs) by downregulating TNFAIP3, thereby suppressing proliferation and promoting apoptosis.
| Catalog Number | E5961 |
| Molecular Formula | C31H31ClFN7O2 |
| CAS# | 2131803-75-1 |
| Inchi | InChI=1S/C31H31ClFN7O2/c1-2-39-15-17-40(18-16-39)28(41)19-21-7-11-24(12-8-21)36-31-34-20-26(33)29(38-31)35-23-13-9-22(10-14-23)30(42)37-27-6-4-3-5-25(27)32/h3-14,20H,2,15-19H2,1H3,(H,37,42)(H2,34,35,3 6,38) |
| Inchi Key | AKSIZPIFQAYJGF-UHFFFAOYSA-N |
| SMILES | CCN1CCN(CC1)C(=O)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5Cl)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/zsh-2208.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5961-ZSH-2208-chemical-structure.png |