ZSH-2208
ZSH‐2208 is a RARγ-selective retinoic acid analogue that exhibits potent anti-tumor effects in oesophageal squamous cell carcinoma (ESCC). It inhibits ESCC tumour-repopulating cells (TRCs) by downregulating TNFAIP3, thereby suppressing proliferation and promoting apoptosis.
| Catalog Number | E5961 |
| Molecular Formula | C30H33ClN4O2 |
| CAS# | 2131803-75-1 |
| Inchi | InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1 |
| Inchi Key | QJZRFPJCWMNVAV-HHHXNRCGSA-N |
| SMILES | CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/zsh-2208.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5961-ZSH-2208-chemical-structure.png |