OPB-171775

OPB-171775 functions as a molecular glue, promoting the formation of a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12). This interaction triggers multiple cellular stresses, ultimately leading to cell death. It also demonstrates significant anticancer activity in patient-derived xenograft (PDX) models of Gastrointestinal stromal tumor (GIST).

Price Not Available 100mg OPB-171775 Supplier Page

Catalog Number	E4695
Molecular Formula	C13H16N4O
CAS#	2131210-15-4
Inchi	InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1
Inchi Key	JNAHVYVRKWKWKQ-CYBMUJFWSA-N
SMILES	CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
Size	100mg
Supplier Page	http://www.selleckchem.com/products/opb-171775.html
Additional Information	https://file.selleck.cn/downloads/struct/E4695-OPB-171775-chemical-structure.png