PD184352 (CI-1040)

PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. PD184352 (CI-1040) selectively induces apoptosis.

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Trivial name	N/A
Catalog Number	S1020
Molecular Formula	C17H14ClF2IN2O2
CAS#	212631-79-3
Inchi	InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
Inchi Key	GFMMXOIFOQCCGU-UHFFFAOYSA-N
SMILES	C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/CI-1040-(PD184352).html
Additional Information	https://file.selleck.cn/downloads/struct/CI-1040-PD184352-chemical-structure-S1020.gif