PD184352
A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC50 of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.
| Catalog Number | ABS-047 |
| Alternative Name(s) | CI-1040 |
| CAS# | 212631-79-3 |
| Inchi | InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24) |
| Inchi Key | GFMMXOIFOQCCGU-UHFFFAOYSA-N |
| SMILES | C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/pd184352-item-1511.html |