Vatalanib (PTK787) 2HCl
Vatalanib 2HCl (PTK787, ZK 222584, cpg-79787) is an inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. Phase 3.
Trivial name | ZK 222584 (cpg-79787) 2HCl |
Catalog Number | S1101 |
Molecular Formula | C10H12N5Na2O8P |
CAS# | 212141-51-0 |
Inchi | InChI=1S/C10H14N5O8P.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18);;/q;2*+1/p-2/t3-,5-,6-,9-;;/m1../s1 |
Inchi Key | PVBRXXAAPNGWGE-LGVAUZIVSA-L |
SMILES | C1=NC2=C(N1C3C(C(C(O3)COP(=O)([O-])[O-])O)O)N=C(NC2=O)N.[Na+].[Na+] |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/Vatalanib,Dihydrochloride-Salt.html |
Additional Information | https://file.selleck.cn/downloads/struct/Vatalanib-PTK787-chemical-structure-S1101.gif |