WHI-P154
WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
| Trivial name | N/A |
| Catalog Number | S2867 |
| Molecular Formula | C16H14BrN3O3 |
| CAS# | 211555-04-3 |
| Inchi | InChI=1S/C16H14BrN3O3/c1-22-14-6-10-12(7-15(14)23-2)18-8-19-16(10)20-9-3-4-13(21)11(17)5-9/h3-8,21H,1-2H3,(H,18,19,20) |
| Inchi Key | CBIAKDAYHRWZCU-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/whi-p154.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WHI-P154-chemical-structure-s2867.gif |