JNJ-63576253 (TRC-253)
JNJ-63576253 (TRC-253) is a potent and selective androgen receptor (AR) Antagonist with IC50 of 6.9 nM. JNJ-63576253 displays robust inhibition in WT and LBD-mutated, enzalutamide-resistant models of prostate cancer.
Trivial name | N/A |
Catalog Number | S9900 |
Molecular Formula | C₂₃H₂₂ClF₃N₆O₂S |
CAS# | 2110428-64-1 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | Cl.FC(F)(F)C1=CC(=CN=C1C#N)N2C(=O)C3(CCC3)N(C2=S)C4=CN=C(OC5CCNCC5)C=C4 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/jnj-63576253-trc-253.html |
Additional Information | https://file.selleck.cn/downloads/struct/s9900-jnj-63576253-trc-253--chemical-structure.gif |