Z-IETD-FMK
Z-IETD-FMK is a selective and cell permeable caspase 8 inhibitor. It also inhibits caspase-10. The bis-methyl ester of Z-IETD-FMK blocked CD95-induced apoptosis.
| Catalog Number | HB00018 |
| Alternative Name(s) | IETD (Modifications: N-terminal benzyloxycarbonyl, C-terminal FMK, Glu-2 = Glu(OMe), Asp-4 = Asp(OMe)) |
| Molecular Formula | C30H43FN4O11 |
| CAS# | 210344-98-2 |
| Purity | >98% |
| Inchi | InChI=1S/C30H43FN4O11/c1-6-17(2)25(35-30(43)46-16-19-10-8-7-9-11-19)28(41)32-20(12-13-23(38)44-4)27(40)34-26(18(3)36)29(42)33-21(22(37)15-31)14-24(39)45-5/h7-11,17-18,20-21,25-26,36H,6,12-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,40)(H,35,43)/t17-,18+,20-,21-,25-,26-/m0/s1 |
| Inchi Key | PHLCQASLWHYEMX-DEKIMQJDSA-N |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1 |
| Size | Inquiry |
| Supplier Page | https://www.creative-peptides.com/product/z-ietd-fmk-item-hb00018-889.html |