Enpatoran
Enpatoran is a potent, selective inhibitor of Toll-like receptors 7 and 8 (TLR7/8), with IC50 of 11.1 nM and 24.1 nM, respectively, in HEK293 cells. It also demonstrates potential for treating autoimmune diseases.
| Trivial name | M5049 |
| Catalog Number | E5922 |
| Molecular Formula | C35H58O9 |
| CAS# | 2101938-42-3 |
| Inchi | InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3 /b14-12-,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33?,35+/m0/s1 |
| Inchi Key | XDHNQDDQEHDUTM-MKFMMVOISA-N |
| SMILES | CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)O)O)O)OC)C |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/enpatoran.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5922-Enpatoran-chemical-structure.png |